当前位置: 首页 - 陈国勋 副教授
浏览量 : 1659

陈国勋,美国田纳西大学诺克斯维尔分校教育、健康和人类科学学院营养学系副教授(终身教授)。

联系方式:Tel: (865) 974-6257, Fax: (865) 974-349

                  E-mail: guoxunc@yahoo.com; gchen6@utk.edu


教育及工作经历:

1986年:武汉大学理学学士;

1989年:武汉大学病毒学与分子生物学,硕士;

2001年:达拉斯德克萨斯大学西南医学中心生物化学和分子生物学博士。

1986-1989年:武汉大学研究生院病毒分子生物学研究生助理

1989-1995年:湖北医学科学院病毒研究所研究员

1995-2001:达拉斯德克萨斯大学西南医学中心,生物化学系吉福德实验室及试金石中心糖尿病研究研究生助理

2001- 2006年7月:达拉斯的德克萨斯大学西南医学中心分子遗传学系,博士后研究员

2006-2012年:田纳西大学诺克斯维尔分校,教育、健康和人类科学学院营养学系助理教授

2012年至今:美国田纳西大学诺克斯维尔分校教育、健康和人类科学学院营养学系副教授(终身教授)


代表性著作

文献:

1.Chen G. Assaying of TGFs Produced by MA782/5s-8101 Mouse Mammary Tumor Cell Line.  (1988)  The  Postgraduate Journal of Wuhan University.  1:93-95.

2.Chen, G. and Li, W.X., (1989)  Studies of Cell Growth Stimulating Factors in Malignant Lung Adenocarcinoma Pleural Effusions.  The Cancer Research on Prevention and Treatment, 16:200-202.

3. Yuan, X., Chen, G. and. Li, W.X.,  (1989) In Vitro Antitumor Action of Salvia Chinese Bent to Human Stomach and Pharyngeal Carcinoma Cells.  The Cancer Research on Prevention and Treatment, 16:7-9.

4.Chen, G., Koyama, K., Yuan, X., Lee, Y., Zhou, Y.-T., O’Doherty, R., Newgard, C.B., and Unger, R.H., (1996)  Disappearance of Body Fat in Normal Rats Induced by Adenovirus-Mediated Leptin Gene Therapy. Proceedings of the National Academy of Sciences USA 93:14795-14799.

5.Koyama, K., Chen, G., Wang, M.-Y., Lee, Y.H., Shimabukuro, M., Newgard, C.B., and Unger, R.H.. (1997)  ß-Cell Function in Normal Rats Made Chronically Hyperleptinemia by Adenovirus-Leptin Gene Therapy. Diabetes 46:1276-1280.

6. Shimabukuro, M., Koyama, K., Chen, G., Wang, M.-Y., Trieu, F., Lee, Y., Newgard, C.B., and Unger, RH. (1997)  Direct Antidiabetic Effect of Leptin through Triglyceride Depletion of Tissue. Proceedings of the National Academy of Sciences USA 94:4637-4641.

7. Koyama, K., Chen, G., Lee, Y., and Unger, R.H. (1997) Tissue Triglycerides, Insulin Resistance and Insulin Production: Implications for Hyperinsulinemia of Obesity. American Journal of Physiology 273:E708-E713.

8. Koyama, K., Shimabukuro, M., Chen, G., Wang, M.-Y., Lee, Y., Kalra, P.S., Dube, M.G., Kalra, S.P., Newgard, C.B., and Unger, R.H. (1998) Resistance to Adenovirally Induced Hyperleptinemia in Rats: Comparison of Ventromedial Hypothalamic Lesions with Mutated Leptin Receptors. The Journal of Clinical Investigation 102:728-733.

9.Hohmeier, H., Mulder, H., Chen, G., Henkel-Reiger, R., Prentki, M., and Newgard, C.B.  (2000) Isolation of INS-1-Derived Cell Lines With Robust KATP Channel-Dependent and -Independent Glucose-Stimulated Insulin Secretion.  Diabetes 49:424-430.

10. Chen, G., Hohmeier, H., Gasa, R., Tran, V., and Newgard, C.B.  (2000)  Selection of Insulinoma Cell Lines With Resistance to IL-1ß and IFN-g-Induced Cytotoxicity.  Diabetes: 49:562-570.

11.Chen, G., Hohmeier, H., and Newgard, C.B. (2001) Expression of the Transcription Factor STAT-1a in Insulinoma Cells Protects Against Cytotoxic Effects of Multiple Cytokines. The Journal of Biological Chemistry 276: 766-772.

书籍:

  1.  Li, Y., Li, R., and Chen, G., Vitamin A’s role in the regulation of hepatic glucose and lipid metabolism during the transition from fasting to refeeding, Handbook of Famine, Starvation, and Nutrient Deprivation edited by V.R. Preedy, and V.B. Patel (eds.), Springer International Publishing AG 2018.    

  2. Li, R., and Chen, G., The story of fortified sugar to combat vitamin A deficiency in Central America, Case Studies of Global Health Issues (Chinese) edited by Xiaohui Liang and Zhongfu Mao, Science Press (China) 2018